Hyperthyroidism in Growth Hormone Deficient Children Treated with Human Growth Hormone
نویسندگان
چکیده
منابع مشابه
Growth hormone treatment in non-growth hormone-deficient children
Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA technology, researchers started to explore new modalities to treat GHD children, as well as to treat a number of other non-GHD conditions. Although with so...
متن کاملOptimization of growth hormone therapy in growth hormone deficient children.
Successful treatment with human growth hormone (hGH) was initially reported by Raben in 19581. Although itis well established that pituitary derived or biosynthetic hGH increases the growth rate in growth hormone deficient children, many patients that were treated in the early days have not reached their target height, or attained adult height below the third percentile of population standards ...
متن کاملClinical studies with recombinant-DNA-derived methionyl human growth hormone in growth hormone deficient children.
Thirty-six children with growth hormone deficiency were treated for up to 48 months with methionyl human growth hormone (hGH) synthesised by DNA recombinant methods. The growth rate for these children increased from 3.2 +/- 1.1 cm/yr to 10.5 +/- 2.2 cm/yr (mean +/- SD). This was similar to the effect of pituitary hGH in ten GH deficient children, 3.8 +/- 1.0 to 10.1 +/- 1.1 cm/yr. Serum somatom...
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there are numerous, often contradictory reports on the effect of growth hormone (gh) therapy on thyroid function. these reports prompted us to evaluate the impact of gh therapy on thyroid function in previously euthyroid children with gh deficiency. twenty five clinically and biochemically euthyroid children with gh deficiency were studied. a thyroid profile (t4, free t4, t3 and tsh) was perfor...
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REFERENCES Benzing, G., III, Schubert, W., Hug, G., and Kaplan, S. (1969). Simultaneous hypoglycemia and acute congestive heart failure. Circulation, 40, 209. Burnard, E. D., and James, L. S. (1961a). The cardiac silhouette in newborn infants: a cinematographic study of the normal range. Pediatrics, 27, 713. -, and(1961b). Failure of the heart after undue asphyxia at birth. Pediatrics, 28, 545....
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ژورنال
عنوان ژورنال: Clinical Pediatric Endocrinology
سال: 1995
ISSN: 0918-5739,1347-7358
DOI: 10.1297/cpe.4.supple6_121